High specificity of cphA-encoded metallo-beta-lactamase from Aeromonas hydrophila AE036 for carbapenems and its contribution to beta-lactam resistance.

The Aeromonas hydrophila AE036 chromosome contains a cphA gene encoding a metallo-beta-lactamase highly active against carbapenem antibiotics. This enzyme was induced in strain AE036 to the same extent by both benzylpenicillin and imipenem. When the cphA gene was inserted into plasmid pACYC184, used...

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Autores principales: Segatore, B, Massidda, O, Satta, G, Setacci, D, Amicosante, G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC187960/
https://ncbi.nlm.nih.gov/pubmed/8328781
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