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Clonal viability measurements on Plasmodium falciparum to assess in vitro schizonticidal activity of leupeptin, chloroquine, and 5-fluoroorotate.

Until now, the in vitro activity of potential antimalarial agents has been evaluated primarily by monitoring decreases in parasite proliferation. These traditional assays do not distinguish between compounds that arrest proliferation of parasites and compounds that kill them. In this report, a more...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Young, R D, Rathod, P K
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187909/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8517698/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.5.1102
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