Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

Frontotemporal dementia with parkinsonism chromosome 17 type (FTDP-17) is caused by mutations in MAPT, the gene encoding tau. FTDP-17 begins with executive function deficits and other abnormal behaviors, which progress to dementia. Neurodegenerative changes include accumulation of aggregated tau as...

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Detaylı Bibliyografya
Asıl Yazarlar: Kraemer, Brian C., Zhang, Bin, Leverenz, James B., Thomas, James H., Trojanowski, John Q., Schellenberg, Gerard D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC187908/
https://ncbi.nlm.nih.gov/pubmed/12872001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1533448100
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