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Specific inhibition of the reverse transcriptase of human immunodeficiency virus type 1 and the chimeric enzymes of human immunodeficiency virus type 1 and type 2 by nonnucleoside inhibitors.

We have studied the effects of four nonnucleoside inhibitors, including the novel natural product inhibitor calanolide A, on molecular chimeras containing complementary segments of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) reverse transcriptases (RTs). All four compounds specifi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Hizi, A, Tal, R, Shaharabany, M, Currens, M J, Boyd, M R, Hughes, S H, McMahon, J B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7685994/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.5.1037
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