Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides.

Ítems similars

• Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
  per: Schinazi, R F, et al.
  Publicat: (1992)
• A novel Met-to-Thr mutation in the YMDD motif of reverse transcriptase from feline immunodeficiency virus confers resistance to oxathiolane nucleosides.
  per: Smith, R A, et al.
  Publicat: (1997)
• Pharmacokinetics, oral bioavailability, and metabolic disposition in rats of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analog active against human immunodeficiency virus and hepatitis B virus.
  per: Frick, L W, et al.
  Publicat: (1993)
• Preclinical and clinical development of the anti-HIV, anti-HBV oxathiolane nucleoside analog emtricitabine
  per: Painter, George R., et al.
  Publicat: (2003)
• The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase.
  per: Wilson, J E, et al.
  Publicat: (1993)