Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides.

The (-) enantiomers of 2',3'-dideoxy-5-fluoro-3'-thiacytidine [(-)-FTC] and 2',3'-dideoxy-3'-thiacytidine [(-)-BCH-189] were recently shown to inhibit selectively human immunodeficiency viruses (HIV) and hepatitis B virus in vitro. In the current study, the potential for HIV type 1 (HIV-1) resistanc...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Schinazi, R F, Lloyd, R M, Nguyen, M H, Cannon, D L, McMillan, A, Ilksoy, N, Chu, C K, Liotta, D C, Bazmi, H Z, Mellors, J W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187791/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7684216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.4.875
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