Protein Kinase Cα-dependent Phosphorylation of the mRNA-stabilizing Factor HuR: Implications for Posttranscriptional Regulation of Cyclooxygenase-2

In this study, we investigated the molecular mechanisms underlying the ATP analogue adenosine-5′-O-(3-thio)triphosphate–induced nucleocytoplasmic shuttling of the mRNA stabilizing factor HuR in human (h) mesangial cells (MC). Using synthetic protein kinase C (PKC) inhibitors and small interfering RN...

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Main Authors: Doller, Anke, Huwiler, Andrea, Müller, Roswitha, Radeke, Heinfried H., Pfeilschifter, Josef, Eberhardt, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2007
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877114/
https://ncbi.nlm.nih.gov/pubmed/17392515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0850
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