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Active Arf6 Recruits ARNO/Cytohesin GEFs to the PM by Binding Their PH Domains
ARNO is a soluble guanine nucleotide exchange factor (GEF) for the Arf family of GTPases. Although in biochemical assays ARNO prefers Arf1 over Arf6 as a substrate, its localization in cells at the plasma membrane (PM) suggests an interaction with Arf6. In this study, we found that ARNO activated Ar...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1877112/ https://ncbi.nlm.nih.gov/pubmed/17409355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-11-0998 |
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