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Acute Traumatic Coagulopathy: Initiated by Hypoperfusion: Modulated Through the Protein C Pathway?

OBJECTIVES: Coagulopathy following major trauma is conventionally attributed to activation and consumption of coagulation factors. Recent studies have identified an acute coagulopathy present on admission that is independent of injury severity. We hypothesized that early coagulopathy is due to tissu...

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Autori principali: Brohi, Karim, Cohen, Mitchell J., Ganter, Michael T., Matthay, Michael A., Mackersie, Robert C., Pittet, Jean-François
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877079/
https://ncbi.nlm.nih.gov/pubmed/17457176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000256862.79374.31
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