Differential Nuclear and Cytoplasmic Expression of PTEN in Normal Thyroid Tissue, and Benign and Malignant Epithelial Thyroid Tumors

Germline mutations in PTEN (MMAC1/TEP1) are found in patients with Cowden syndrome, a familial cancer syndrome which is characterized by a high risk of breast and thyroid neoplasia. Although somatic intragenic PTEN mutations have rarely been found in benign and malignant sporadic thyroid tumors, los...

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Hlavní autoři: Gimm, Oliver, Perren, Aurel, Weng, Liang-Ping, Marsh, Debbie J., Yeh, Jen Jen, Ziebold, Ulrike, Gil, Elad, Hinze, Raoul, Delbridge, Leigh, Lees, Jacqueline A., Mutter, George L., Robinson, Bruce G., Komminoth, Paul, Dralle, Henning, Eng, Charis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2000
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Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876937/
https://ncbi.nlm.nih.gov/pubmed/10793080
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