KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms arising in the gastrointestinal tract. GISTs express the KIT receptor tyrosine kinase, and many cases have activating mutations in the KIT juxtamembrane region. We now report an analysis of KIT cDNA and genomic sequenc...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lux, Marcia L., Rubin, Brian P., Biase, Tara L., Chen, Chang-Jie, Maclure, Timothy, Demetri, George, Xiao, Sheng, Singer, Samuel, Fletcher, Christopher D.M., Fletcher, Jonathan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2000
Soggetti:
Short Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876850/
https://ncbi.nlm.nih.gov/pubmed/10702394
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi