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GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model
Malignant astrocytomas are the most common and lethal adult primary brain tumor. Retroviral gene trapping of nontransformed neonatal astrocytes from a glial fibrillary acidic protein (GFAP):(V12)Ha-Ras murine astrocytoma model led to isolation of the transcription factor Gata6. Loss of Gata6 resulte...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876570/ https://ncbi.nlm.nih.gov/pubmed/17463088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611669104 |
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