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Signatures of hydrophobic collapse in extended proteins captured with force spectroscopy
We unfold and extend single proteins at a high force and then linearly relax the force to probe their collapse mechanisms. We observe a large variability in the extent of their recoil. Although chain entropy makes a small contribution, we show that the observed variability results from hydrophobic i...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876547/ https://ncbi.nlm.nih.gov/pubmed/17470816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702179104 |
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