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A highly efficient form of the selenocysteine insertion sequence element in protozoan parasites and its use in mammalian cells

Selenoproteins are an elite group of proteins containing a rare amino acid, selenocysteine (Sec), encoded by the codon, UGA. In eukaryotes, incorporation of Sec requires a Sec insertion sequence (SECIS) element, a stem–loop structure located in the 3′-untranslated regions of selenoprotein mRNAs. Her...

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Detalhes bibliográficos
Main Authors: Novoselov, Sergey V., Lobanov, Alexey V., Hua, Deame, Kasaikina, Marina V., Hatfield, Dolph L., Gladyshev, Vadim N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876537/
https://ncbi.nlm.nih.gov/pubmed/17470795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610683104
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