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Pseudomonas aeruginosa and sPLA(2) IB stimulate ABCA1-mediated phospholipid efflux via ERK-activation of PPARα–RXR

Bacterial infection triggers an acute inflammatory response that might alter phospholipid metabolism. We have investigated the acute-phase response of murine lung epithelia to Pseudomonas aeruginosa infection. Ps. aeruginosa triggered secretion of the pro-inflammatory lipase, sPLA(2) IB (phospholipa...

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Detalhes bibliográficos
Main Authors: Agassandian, Marianna, Miakotina, Olga L., Andrews, Matthew, Mathur, Satya N., Mallampalli, Rama K.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876365/
https://ncbi.nlm.nih.gov/pubmed/17223797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061364
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