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sPLA2 IB induces human podocyte apoptosis via the M-type phospholipase A2 receptor

The M-type phospholipase A2 receptor (PLA2R) is expressed in podocytes in human glomeruli. Group IB secretory phospholipase A2 (sPLA2 IB), which is one of the ligands of the PLA2R, is more highly expressed in chronic renal failure patients than in controls. However, the roles of the PLA2R and sPLA2...

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Detalhes bibliográficos
Main Authors: Pan, Yangbin, Wan, Jianxin, Liu, Yipeng, Yang, Qian, Liang, Wei, Singhal, Pravin C., Saleem, Moin A., Ding, Guohua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205892/
https://ncbi.nlm.nih.gov/pubmed/25335547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06660
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