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CpG Island Methylator Phenotype-Low (CIMP-Low) in Colorectal Cancer: Possible Associations with Male Sex and KRAS Mutations

The CpG island methylator phenotype (CIMP or CIMP-high) with extensive promoter methylation seems to be a distinct epigenotype of colorectal cancer. However, no study has comprehensively examined features of colorectal cancer with less extensive promoter methylation (designated as “CIMP-low”). Using...

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Detalhes bibliográficos
Main Authors: Ogino, Shuji, Kawasaki, Takako, Kirkner, Gregory J., Loda, Massimo, Fuchs, Charles S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876166/
https://ncbi.nlm.nih.gov/pubmed/17065427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2006.060082
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