Domain Regulation of Imprinting Cluster in Kip2/Lit1 Subdomain on Mouse Chromosome 7F4/F5: Large-Scale DNA Methylation Analysis Reveals That DMR-Lit1 Is a Putative Imprinting Control Region

Mouse chromosome 7F4/F5, where the imprinting domain is located, is syntenic to human 11p15.5, the locus for Beckwith-Wiedemann syndrome. The domain is thought to consist of the two subdomains Kip2 (p57(kip2))/Lit1 and Igf2/H19. Because DNA methylation is believed to be a key factor in genomic impri...

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Detalhes bibliográficos
Main Authors: Yatsuki, Hitomi, Joh, Keiichiro, Higashimoto, Ken, Soejima, Hidenobu, Arai, Yuji, Wang, Youdong, Hatada, Izuho, Obata, Yayoi, Morisaki, Hiroko, Zhang, Zhongming, Nakagawachi, Tetsuji, Satoh, Yuji, Mukai, Tsunehiro
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187562/
https://ncbi.nlm.nih.gov/pubmed/12466290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.110702
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