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Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor

Repression of E2F transcription activity by the retinoblastoma (Rb) tumor suppressor through its interaction with the transactivation domain of the E2F transcription factor is one of the central features of G1/S arrest in the mammalian cell cycle. Deregulation of the Rb–E2F interaction results in hy...

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Sonraí Bibleagrafaíochta
Main Authors: Lee, Changwook, Chang, Jeong Ho, Lee, Hyun Sook, Cho, Yunje
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC187509/
https://ncbi.nlm.nih.gov/pubmed/12502741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1046102
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