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Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor
Repression of E2F transcription activity by the retinoblastoma (Rb) tumor suppressor through its interaction with the transactivation domain of the E2F transcription factor is one of the central features of G1/S arrest in the mammalian cell cycle. Deregulation of the Rb–E2F interaction results in hy...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187509/ https://ncbi.nlm.nih.gov/pubmed/12502741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1046102 |
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