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Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor

Repression of E2F transcription activity by the retinoblastoma (Rb) tumor suppressor through its interaction with the transactivation domain of the E2F transcription factor is one of the central features of G1/S arrest in the mammalian cell cycle. Deregulation of the Rb–E2F interaction results in hy...

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Detalhes bibliográficos
Main Authors: Lee, Changwook, Chang, Jeong Ho, Lee, Hyun Sook, Cho, Yunje
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187509/
https://ncbi.nlm.nih.gov/pubmed/12502741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1046102
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