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5′ exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly

A general consequence of pre-mRNA splicing is the stable deposition of several proteins 20–24 nucleotides (nt) upstream of exon–exon junctions on spliced mRNAs. This exon junction complex (EJC) contains factors involved in mRNA export, cytoplasmic localization, and nonsense-mediated mRNA decay. Here...

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Detalles Bibliográficos
Main Authors: Reichert, Vienna L., Le Hir, Hervé, Jurica, Melissa S., Moore, Melissa J.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC187475/
https://ncbi.nlm.nih.gov/pubmed/12414731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1030602
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