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Molecular mechanism of upregulation of survivin transcription by the AT-rich DNA-binding ligand, Hoechst33342: evidence for survivin involvement in drug resistance

We have previously shown that hedamycin, a GC-rich DNA-binding antitumor agent, downregulates survivin transcription (Wu et al. (2005) Molecular mechanism of inhibition of survivin transcription by the GC-rich sequence selective DNA-binding antitumor agent, hedamycin: evidence of survivin downregula...

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Autors principals: Wu, Jianguo, Apontes, Pasha, Song, Lei, Liang, Ping, Yang, Lily, Li, Fengzhi
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874665/
https://ncbi.nlm.nih.gov/pubmed/17392340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm149
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