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Pharmacokinetics, binding and distribution of Hoechst 33342 in spheroids and murine tumours.

The fluorescent stain Hoechst 33342, when injected i.v. into mice, has an LD50 of 300 micrograms g-1. The stain exits rapidly from the blood, with a half-life of 110 sec following an injection of 10 micrograms g-1, but remains bound within target cells, redistributing with a half-life longer than 2...

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Bibliografski detalji
Glavni autori: Olive, P. L., Chaplin, D. J., Durand, R. E.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1985
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977212/
https://ncbi.nlm.nih.gov/pubmed/4063148
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