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Beyond the 3′ end: experimental validation of extended transcript isoforms

High throughput EST and full-length cDNA sequencing have revealed extensive variations at the 3′ ends of mammalian transcripts. Whether all of these changes are biologically meaningful has been the subject of controversy, as such, results may reflect in part transcription or polyadenylation leakage....

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Bibliografiske detaljer
Main Authors: Moucadel, Virginie, Lopez, Fabrice, Ara, Takeshi, Benech, Philippe, Gautheret, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874610/
https://ncbi.nlm.nih.gov/pubmed/17339231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm062
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