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Differential Repression of Alternative Transcripts: A Screen for miRNA Targets

Alternative polyadenylation sites produce transcript isoforms with 3′ untranslated regions (UTRs) of different lengths. If a microRNA (miRNA) target is present in the UTR, then only those target-containing isoforms should be sensitive to control by a cognate miRNA. We carried out a systematic examin...

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Autors principals: Legendre, Matthieu, Ritchie, William, Lopez, Fabrice, Gautheret, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458965/
https://ncbi.nlm.nih.gov/pubmed/16699595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0020043
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