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Deregulated G(1)-cyclin expression induces genomic instability by preventing efficient pre-RC formation

Although genomic instability is a hallmark of human cancer cells, the mechanisms by which genomic instability is generated and selected for during oncogenesis remain obscure. In most human cancers, the pathway leading to the activation of the G(1) cyclins is deregulated. Using budding yeast as a mod...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:Genes Dev
Үндсэн зохиолчид: Tanaka, Seiji, Diffley, John F.X.
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Cold Spring Harbor Laboratory Press 2002
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187461/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12381663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1011002
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