Deregulated G(1)-cyclin expression induces genomic instability by preventing efficient pre-RC formation
Although genomic instability is a hallmark of human cancer cells, the mechanisms by which genomic instability is generated and selected for during oncogenesis remain obscure. In most human cancers, the pathway leading to the activation of the G(1) cyclins is deregulated. Using budding yeast as a mod...
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| Udgivet i: | Genes Dev |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187461/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12381663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1011002 |
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