Deregulated G(1)-cyclin expression induces genomic instability by preventing efficient pre-RC formation

Although genomic instability is a hallmark of human cancer cells, the mechanisms by which genomic instability is generated and selected for during oncogenesis remain obscure. In most human cancers, the pathway leading to the activation of the G(1) cyclins is deregulated. Using budding yeast as a mod...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Genes Dev
Hauptverfasser:	Tanaka, Seiji, Diffley, John F.X.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2002
Schlagworte:	Research Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187461/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12381663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1011002
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!