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Pharmacokinetics and anticonvulsant effects of diazepam in children with severe falciparum malaria and convulsions

AIMS: Convulsions are a common complication of severe malaria in children and are associated with poor outcome. Diazepam is used to terminate convulsions but its pharmacokinetics and pharmacodynamics have not been studied in this group. Accordingly, we carried out a comparative study of the pharmaco...

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Autors principals: Ogutu, B R, Newton, C R J C, Crawley, J, Muchohi, S N, Otieno, G O, Edwards, G, Marsh, K, Kokwaro, G O
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874558/
https://ncbi.nlm.nih.gov/pubmed/11849195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01529.x
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