Pharmacokinetics and clinical effect of phenobarbital in children with severe falciparum malaria and convulsions

AIMS: Phenobarbital is commonly used to treat status epilepticus in resource-poor countries. Although a dose of 20 mg kg(−1) is recommended, this dose, administered intramuscularly (i.m.) for prophylaxis, is associated with an increase in mortality in children with cerebral malaria. We evaluated a 1...

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Autores principales: Kokwaro, Gilbert O, Ogutu, Bernhards R, Muchohi, Simon N, Otieno, Godfrey O, Newton, Charles R J C
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2003
Materias:
Short Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884365/
https://ncbi.nlm.nih.gov/pubmed/12968992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01951.x
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