Development and validation of limited sampling strategies for prediction of the systemic exposure to the novel anticancer agent E7070 (N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide)

AIMS: E7070 is a novel, sulphonamide anticancer agent currently under clinical development for the treatment of solid tumours. The aim of this study was to develop and validate limited sampling strategies for the prediction of E7070 exposure in two different treatment schedules for phase II studies...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: van Kesteren, Charlotte, Mathôt, R A A, Raymond, E, Armand, J P, Fumoleau, P, Punt, C, Ravic, M, Wanders, J, Beijnen, J H, Schellens, J H M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2002
Pynciau:
Pharmacokinetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874478/
https://ncbi.nlm.nih.gov/pubmed/12445024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01684.x
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