Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism

AIMS: Previously, we determined the phenotyping of in vivo nicotine metabolism and the genotyping of the CYP2A6 gene (CYP2A6*1 A, CYP2A6*1B, CYP2A6*2, CYP2A6*3, CYP2A6*4 and CYP2A6*5) in 92 Japanese and 209 Koreans. In the study, we found one Korean and four Japanese subjects genotyped as CYP2A6*1B/...

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Detalhes bibliográficos
Main Authors: Yoshida, Ryoko, Nakajima, Miki, Watanabe, Yuki, Kwon, Jun-Tack, Yokoi, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Drug Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874463/
https://ncbi.nlm.nih.gov/pubmed/12445030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01667.x
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