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Nodal activity in the node governs left-right asymmetry

Nodal is expressed at the lateral edges of the mouse node, but its function in this “organizer” tissue remains unknown due to the early lethality of Nodal mutant embryos. Here we used a genetic strategy to selectively remove Nodal activity from the node. Embryos lacking Nodal in the node fail to ini...

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Bibliografiske detaljer
Main Authors: Brennan, Jane, Norris, Dominic P., Robertson, Elizabeth J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC187443/
https://ncbi.nlm.nih.gov/pubmed/12231623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1016202
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