Notch activity induces Nodal expression and mediates the establishment of left–right asymmetry in vertebrate embryos

Left-sided expression of Nodal in the lateral plate mesoderm is a conserved feature necessary for the establishment of normal left–right asymmetry during vertebrate embryogenesis. By using gain- and loss-of-function experiments in zebrafish and mouse, we show that the activity of the Notch pathway i...

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Veröffentlicht in:	Genes Dev
Hauptverfasser:	Raya, Ángel, Kawakami, Yasuhiko, Rodríguez-Esteban, Concepción, Büscher, Dirk, Koth, Christopher M., Itoh, Tohru, Morita, Masanobu, Raya, R. Marina, Dubova, Ilir, Bessa, Joaquín Grego, de la Pompa, José Luis, Belmonte, Juan Carlos Izpisúa
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2003
Schlagworte:	Research Communication
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1084403
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