Notch activity induces Nodal expression and mediates the establishment of left–right asymmetry in vertebrate embryos

Left-sided expression of Nodal in the lateral plate mesoderm is a conserved feature necessary for the establishment of normal left–right asymmetry during vertebrate embryogenesis. By using gain- and loss-of-function experiments in zebrafish and mouse, we show that the activity of the Notch pathway i...

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Bibliografiske detaljer
Main Authors: Raya, Ángel, Kawakami, Yasuhiko, Rodríguez-Esteban, Concepción, Büscher, Dirk, Koth, Christopher M., Itoh, Tohru, Morita, Masanobu, Raya, R. Marina, Dubova, Ilir, Bessa, Joaquín Grego, de la Pompa, José Luis, Belmonte, Juan Carlos Izpisúa
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2003
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196060/
https://ncbi.nlm.nih.gov/pubmed/12730123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1084403
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