Pharmacokinetic/pharmacodynamic model for prednisolone inhibition of whole blood lymphocyte proliferation

AIMS: Mitogen-induced ex vivo whole blood lymphocyte proliferation (WBLP) is a widely used method to assess lymphocyte responsiveness to immunosuppressive therapy. A three-component complex model was developed to characterize effects of prednisolone on cell trafficking, transduction, and lymphocyte...

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Autors principals: Magee, Mindy He, Blum, Robert A, Lates, Christian D, Jusko, William J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
Matèries:
Pharmacokinetics/Pharmacodynamics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874371/
https://ncbi.nlm.nih.gov/pubmed/11994053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01567.x
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