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The effects of rifampicin on the pharmacokinetics and pharmacodynamics of orally administered nilvadipine to healthy subjects

AIMS: To study the effects of rifampicin on the pharmacokinetics and pharmacodynamics of nilvadipine. METHODS: Five healthy adult volunteers received nilvadipine (4 mg) orally before and after a 6 day treatment with rifampicin. Blood and urine were collected and assayed for plasma nilvadipine and ur...

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Bibliographic Details
Main Authors: Saima, S, Furuie, K, Yoshimoto, H, Fukuda, J, Hayashi, T, Echizen, H
Format: Artigo
Language:Inglês
Published: Blackwell Science Ltd 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874299/
https://ncbi.nlm.nih.gov/pubmed/11851646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01545.x
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