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Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets
SFKs (Src family kinases) contribute importantly to platelet function in haemostasis. SFK activity is controlled by Csk (C-terminal Src kinase), which phosphorylates a C-terminal tyrosine residue on SFKs, resulting in inhibition of SFK activity. Csk is recruited to sites of SFK activity by tyrosine-...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Portland Press Ltd.
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1874248/ https://ncbi.nlm.nih.gov/pubmed/17233630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061618 |
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