Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets

SFKs (Src family kinases) contribute importantly to platelet function in haemostasis. SFK activity is controlled by Csk (C-terminal Src kinase), which phosphorylates a C-terminal tyrosine residue on SFKs, resulting in inhibition of SFK activity. Csk is recruited to sites of SFK activity by tyrosine-...

Full description

Saved in:
Bibliographic Details
Main Authors: Rathore, Vipul B., Okada, Masato, Newman, Peter J., Newman, Debra K.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874248/
https://ncbi.nlm.nih.gov/pubmed/17233630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061618
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items