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Regulation of the Src Family Kinases by Csk

The non-receptor tyrosine kinase Csk serves as an indispensable negative regulator of the Src family tyrosine kinases (SFKs) by specifically phosphorylating the negative regulatory site of SFKs, thereby suppressing their oncogenic potential. Csk is primarily regulated through its SH2 domain, which i...

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Détails bibliographiques
Auteur principal: Okada, Masato
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492796/
https://ncbi.nlm.nih.gov/pubmed/23139636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.5141
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