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Regulation of the Src Family Kinases by Csk
The non-receptor tyrosine kinase Csk serves as an indispensable negative regulator of the Src family tyrosine kinases (SFKs) by specifically phosphorylating the negative regulatory site of SFKs, thereby suppressing their oncogenic potential. Csk is primarily regulated through its SH2 domain, which i...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Ivyspring International Publisher
2012
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3492796/ https://ncbi.nlm.nih.gov/pubmed/23139636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.5141 |
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