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Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1

Insulin stimulation of the trafficking of the glucose transporter GLUT4 to the plasma membrane is controlled in part by the phosphorylation of the Rab GAP (GTPase-activating protein) AS160 (also known as Tbc1d4). Considerable evidence indicates that the phosphorylation of this protein by Akt (protei...

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Autores principales: Roach, William G., Chavez, Jose A., Mîinea, Cristinel P., Lienhard, Gustav E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874243/
https://ncbi.nlm.nih.gov/pubmed/17274760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061798
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