Human Cytomegalovirus US2 Causes Similar Effects on Both Major Histocompatibility Complex Class I and II Proteins in Epithelial and Glial Cells

The human cytomegalovirus (HCMV) glycoprotein US2 specifically binds to major histocompatibility complex (MHC) class I heavy chain (HC) and class II proteins DRα and DMα, triggering their degradation by proteasomes. Effects of US2 on class II proteins were originally characterized in HCMV- or adenov...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hegde, Nagendra R., Johnson, David C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12915544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.17.9287-9294.2003
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