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Human Cytomegalovirus US2 Causes Similar Effects on Both Major Histocompatibility Complex Class I and II Proteins in Epithelial and Glial Cells

The human cytomegalovirus (HCMV) glycoprotein US2 specifically binds to major histocompatibility complex (MHC) class I heavy chain (HC) and class II proteins DRα and DMα, triggering their degradation by proteasomes. Effects of US2 on class II proteins were originally characterized in HCMV- or adenov...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Hegde, Nagendra R., Johnson, David C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187418/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12915544/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.17.9287-9294.2003
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