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Human Cytomegalovirus US2 Causes Similar Effects on Both Major Histocompatibility Complex Class I and II Proteins in Epithelial and Glial Cells

The human cytomegalovirus (HCMV) glycoprotein US2 specifically binds to major histocompatibility complex (MHC) class I heavy chain (HC) and class II proteins DRα and DMα, triggering their degradation by proteasomes. Effects of US2 on class II proteins were originally characterized in HCMV- or adenov...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Hegde, Nagendra R., Johnson, David C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187418/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12915544/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.17.9287-9294.2003
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