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The time of maximum effect for model selection in pharmacokinetic– pharmacodynamic analysis applied to frusemide

AIMS: Both indirect-response models and effect-compartment models are used to describe the pharmacodynamics of drugs when there is a delay in the time course of the pharmacological effect in relation to the concentration of the drug. The aim of this study was to investigate whether the time of maxim...

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Detalhes bibliográficos
Principais autores: Wakelkamp, Monique, Alván, Gunnar, Paintaud, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873996/
https://ncbi.nlm.nih.gov/pubmed/9489596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00637.x
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