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Concurrent administration of donepezil HCl and theophylline: assessment of pharmacokinetic changes following multiple-dose administration in healthy volunteers

AIM: The aim of the study was to evaluate the pharmacokinetics of theophylline administered alone, and in combination with donepezil HCl, following multiple-dose administration of both drugs in healthy volunteers. METHODS: This was an open-label, randomized, two-period crossover study in healthy mal...

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Detalhes bibliográficos
Main Authors: Tiseo, P J, Foley, K, Friedhoff, L T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873816/
https://ncbi.nlm.nih.gov/pubmed/9839764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.0460s1035.x
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