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Pharmacokinetic and pharmacodynamic profile of donepezil HCl following evening administration

AIMS: The primary objective of this study was to characterize the pharmacokinetics and pharmacodynamics of single daily doses of donepezil (5 and 10 mg) each evening for 28 consecutive days. A secondary objective was to measure the plasma protein binding of donepezil at steady state. METHODS: This w...

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Библиографические подробности
Главные авторы: Tiseo, P J, Rogers, S L, Friedhoff, L T
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 1998
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873813/
https://ncbi.nlm.nih.gov/pubmed/9839760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.0460s1013.x
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