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Concurrent administration of donepezil HCl and ketoconazole: assessment of pharmacokinetic changes following single and multiple doses

AIM: The aim of this study was to examine the pharmacokinetics of donepezil HCl and ketoconazole separately, and in combination, following administration of single and multiple oral doses. METHODS: This was an open-label, randomized, three-period crossover study in healthy volunteers (n = 21). Durin...

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Detalhes bibliográficos
Main Authors: Tiseo, P J, Perdomo, C A, Friedhoff, L T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873808/
https://ncbi.nlm.nih.gov/pubmed/9839763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.0460s1030.x
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