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Halofantrine and chloroquine inhibit CYP2D6 activity in healthy Zambians
AIMS: To determine the effect of therapeutic loading doses of halofantrine and chloroquine on CYP2D6 activity in healthy black Zambians. METHODS: Twenty healthy black male Zambians were phenotyped for CYP2D6 activity by measuring the debrisoquine/4-hydroxydebrisoquine ratio in a 0–8 h urine sample a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1873379/ https://ncbi.nlm.nih.gov/pubmed/10896408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00671.x |
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