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Nicotinamide Ribosyl Uptake Mutants in Haemophilus influenzae

The gene for the nicotinamide riboside (NR) transporter (pnuC) was identified in Haemophilus influenzae. A pnuC mutant had only residual NR uptake and could survive in vitro with high concentrations of NR, but could not survive in vivo. PnuC may represent a target for the development of inhibitors f...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Herbert, Mark, Sauer, Elizabeta, Smethurst, Graeme, Kraiβ, Anita, Hilpert, Anna-Karina, Reidl, Joachim
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187334/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12933892/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.9.5398-5401.2003
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