Nicotinamide Ribosyl Uptake Mutants in Haemophilus influenzae

The gene for the nicotinamide riboside (NR) transporter (pnuC) was identified in Haemophilus influenzae. A pnuC mutant had only residual NR uptake and could survive in vitro with high concentrations of NR, but could not survive in vivo. PnuC may represent a target for the development of inhibitors f...

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Главные авторы: Herbert, Mark, Sauer, Elizabeta, Smethurst, Graeme, Kraiβ, Anita, Hilpert, Anna-Karina, Reidl, Joachim
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
Предметы:
Molecular Pathogenesis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC187334/
https://ncbi.nlm.nih.gov/pubmed/12933892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.9.5398-5401.2003
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